| | Editor's Essential Reading  Clinical Advances in Liver, Pancreas, and Biliary TractAnna S. Lok, Richard K. Sterling, James E. Everhart, Elizabeth C. Wright, John C. Hoefs, Adrian M. Di Bisceglie, Timothy R. Morgan, Hae–Young Kim, William M. Lee, Herbert L. Bonkovsky, Jules L. Dienstag, HALT-C Trial Group
The outcome of patients with hepatocellular carcinoma (HCC) remains poor because of late diagnosis. The aim of this study was to compare the accuracy of a-fetoprotein (AFP) and des-α-carboxy prothrombin (DCP) in the early diagnosis of HCC. Among 1031 patients randomized in the Hepatitis C Antiviral Long-term Treatment Against Cirrhosis (HALT-C) Trial, a nested case-control study of 39 HCC cases (24 early stage) and 77 matched controls was conducted to compare the performance of AFP and DCP. Testing was performed on sera from 12 months prior (month -12) to the time of HCC diagnosis (month 0).
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Gastroenterology, the official journal of the AGA Institute, is the number one journal in the field of gastrointestinal disease and ranks in the top one percent of all biomedical journals.
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| Issue HighlightsClinical—Alimentary Tract |  |
Filip Baert, Liesbeth Moortgat, Gert Van Assche, Philip Caenepeel, Philippe Vergauwe, Martine De Vos, Pieter Stokkers, Daniel Hommes, Paul Rutgeerts, Severine Vermeire, Geert D'Haens, Belgian Inflammatory Bowel Disease Research Group, North-Holland Gut Club
| Clinical Advances in Liver, Pancreas, and Biliary Tract |  |
Gerhard E. Feurle, Natascha S. Junga, Thomas Marth
| Clinical Advances in Liver, Pancreas, and Biliary Tract | |
Peter Ferenci, Hermann Laferl, Thomas–Matthias Scherzer, Andreas Maieron, Harald Hofer, Rudolf Stauber, Michael Gschwantler, Harald Brunner, Christoph Wenisch, Martin Bischof, Michael Strasser, Christian Datz, Wolfgang Vogel, Karin Löschenberger, Petra Steindl–Munda, Austrian Hepatitis Study Group
| Basic—Alimentary Tract |  |
Chang Xiao, Sally A. Ogle, Michael A. Schumacher, Melissa A. Orr–Asman, Marian L. Miller, Nantaporn Lertkowit, Andrea Varro, Frederic Hollande, Yana Zavros
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Edwin F. de Zoeten, Liqing Wang, Hong Sai, Wolfgang H. Dillmann, Wayne W. Hancock
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Meghna Waghray, Yana Zavros, Milena Saqui–Salces, Mohamad El–Zaatari, C. Bharath Alamelumangapuram, Andrea Todisco, Kathryn A. Eaton, Juanita L. Merchant
| Basic—Liver, Pancreas, and Biliary Tract | |
Jelena Mann, David C.K. Chu, Aidan Maxwell, Fiona Oakley, Nian–Ling Zhu, Hidekazu Tsukamoto, Derek A. Mann
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Chihiro Morishima, Margaret C. Shuhart, Chia C. Wang, Denise M. Paschal, Minjun C. Apodaca, Yanze Liu, Derek D. Sloan, Tyler N. Graf, Nicholas H. Oberlies, David Y.–W. Lee, Keith R. Jerome, Stephen J. Polyak
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Fook–Hong Ng, Siu–Yin Wong, Kwok–Fai Lam, Wai–Ming Chu, Pierre Chan, Yuk–Hei Ling, Carolyn Kng, Wai–Cheung Yuen, Yuk–Kong Lau, Ambrose Kwan, Benjamin C.Y. Wong
Paul Kuo, Steven Pieterse, Hugh A. Harley
Stefan Zeuzem
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Top 20 Most Cited Articles | |
|  | | Gastroenterology in the News
Gastroenterology has been featured in The New York Times, The New York Times Well Blog, the Guardian, Reuters, and on NPR!
AGA Journal Club
AGA members can now rate and comment on select articles from Gastroenterology and CGH by joining the AGA Journal Club. Read compelling commentary provided by club leaders Drs. Geoffrey L. Braden and Ingram M. Roberts. Join now to participate in lively discussions about the ground-breaking research advancing the field of GI. Read recent press releases.
New Gastrointestinal Endoscopy Course at Penn
Obtain the necessary tools and techniques for the endoscopic management of digestive and related disorders by attending the 3rd annual “Penn Live: GI Endoscopy and Liver Disease 2010” CME-certified course. The course is hosted by the University of Pennsylvania’s Department of Medicine, Division of Gastroenterology. Click here for more details.
Thank You to Our 2009 Reviewers
The AGA Institute journals thank their 2009 reviewers for their invaluable input and expertise. To view a full listing of individuals who reviewed for the journal in 2009 click here.
Wanted: Editor-in-Chief for Gastroenterology
Applications due April 1, 2010. Term begins July 1, 2011. Read more.
New! Gastroenterology Supplemental Issue on Micronutrient Dosing
Read the November 2009 supplement to Gastroenterology, "Micronutrients in Parenteral Nutrition: Too Little or Too Much?". Based on proceedings from this year's annual American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Research Workshop, leading international experts present the latest information on correct dosages of parenteral vitamins and trace elements. AGA Institute Course on Sedation
To learn more about the administration of sedation, attend the AGA Institute’s course, Sedation Competencies for the Endoscopy Team: A Hands-on Course for Gastroenterologists and Nurses on Jan. 17, 2010 in Las Vegas. View details at www.gilearn.org/sedationcourse.
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Readers of Gastroenterology and Clinical Gastroenterology and Hepatology (CGH) can now keep abreast of the journals' most recent and compelling research via the convenience of Facebook. Click here to learn more. More news and announcements |
Review
Resistance to Direct Antiviral Agents in Patients With Hepatitis C Virus Infection
Christoph Sarrazin, Stefan Zeuzem
Chronic hepatitis C virus (HCV) infection is one of the major causes of cirrhosis, hepatocellular carcinoma, and liver failure that leads to transplantation. The current standard treatment, a combination of pegylated interferon alfa and ribavirin, eradicates the virus in only about 50% of patients.
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Imaging and Advanced Technology |
Editorial
The Role of Bile Acids in Gallstone-Induced Pancreatitis
Markus M. Lerch, Ali A. Aghdassi
It is well established that, once a gallstone begins to migrate through the biliary tract, it poses a risk for developing pancreatitis. The question remains how gallstones cause pancreatitis during their passage towards the duodenum.
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